Cabello-Yeves, P. J., Zemskaya, T. I., Rosselli, R., Coutinho, F. H., Zakharenko, A. S., Blinov,
V. V., & Rodriguez-Valera, F. 2017. Genomes of novel microbial lineages assembled from the
sub-ice waters of Lake Baikal. Applied and Environmental Microbiology, 84(1), e02132-17.

Cabello-Yeves, P. J., Ghai, R., Mehrshad, M., Picazo, A., Camacho, A., & Rodriguez-Valera, F.
2017. Reconstruction of Diverse Verrucomicrobial Genomes from Metagenome Datasets of
Freshwater Reservoirs. Frontiers in Microbiology, 8, 2131.

López-Pérez, M., Haro-Moreno, J. M., González-Serrano, R., Parras-Moltó, M., & Rodriguez-
Valera, F. 2017. Genome diversity of marine phages recovered from Mediterranean metagenomes:
Size matters. PLoS Genetics, 13(9), e1007018.

Martinez-Hernandez, F., Fornas, O., Gomez, M. L., Bolduc, B., de La Cruz Peña, M. J., Martínez,
J., Anton, J., Gasol, J. M., Rosselli, R., Rodriguez-Valera, F., Sullivan, M. B., Acinas, S. G. &
Martínez-García, M. 2017. Single-virus genomics reveals hidden cosmopolitan and abundant
viruses. Nature Communications, 8.

Bolhuis, H., Martín-Cuadrado, A. B., Rosselli, R., Pašić, L., & Rodriguez-Valera, F. 2017.
Transcriptome analysis of Haloquadratum walsbyi: vanity is but the surface. BMC genomics,
18(1), 510.

Cabello-Yeves, P. J., Haro-Moreno, J. M., Martin-Cuadrado, A. B., Ghai, R., Picazo, A., Camacho,
A., & Rodriguez-Valera, F. 2017. Novel Synechococcus Genomes Reconstructed from Freshwater
Reservoirs. Frontiers in Microbiology, 8.

Martinez-Hernandez, F., Fornas, O., Lluesma Gómez, M., Bolduc, B., Peña, C., Martínez Martínez,
J., Anton, J., Gasol, J. M., Rosselli, R., Rodriguez-Valera, F., Sullivan, M. B., Acinas, S. G.,
Martinez-Garcia, M. 2017. Single-virus genomics reveals hidden cosmopolitan and abundant
viruses. Nature Communications, DOI: 10.1038

Melnikov, I., Polovinkin, V., Kovalev, K., Gushchin, I., Shevtsov, M., Shevchenko, V., Mishin, A.,
Alekseev, A., Rodriguez-Valera, F. et al.. 2017. Fast iodide-SAD phasing for high-throughput
membrane protein structure determination. Science Advances, 3(5), e1602952.

Haro-Moreno JM, Rodriguez-Valera F, López-García P, Moreira D, Martin-Cuadrado AB.
New insights into marine group III Euryarchaeota, from dark to light. 2017. ISME J. 1-16.
doi: 10.1038/ismej.2016.188.

López-Pérez M, Ramon-Marco N, Rodriguez-Valera F. Networking in microbes: conjugative
elements and plasmids in the genus Alteromonas
2017. BMC Genomics, 18(1), 36.
doi: 10.1186/s12864-016-3461-0


Ghai R, Mehrshad M, Mizuno CM, Rodriguez-Valera F. Metagenomic recovery of
phage genomes of uncultured freshwater actinobacteria. ISME J. 2016 Aug 9. doi:

Mizuno CM, Ghai R, Saghaï A, López-García P, Rodriguez-Valera F. Genomes of
Abundant and Widespread Viruses from the Deep Ocean. MBio. 2016 Jul 26;7(4). pii:
e00805-16. doi: 10.1128/mBio.00805-16.

López-Pérez M, Kimes NE, Haro-Moreno JM, Rodriguez-Valera F. Not All Particles
Are Equal: The Selective Enrichment of Particle-Associated Bacteria from the
Mediterranean Sea. Front Microbiol. 2016 Jun 22;7:996. doi:

Mojica FJ, Rodriguez-Valera F. The discovery of CRISPR in archaea and
bacteria. FEBS J. 2016 Sep;283(17):3162-9. doi: 10.1111/febs.13766.

López-Pérez M, Rodriguez-Valera F. Pangenome Evolution in the Marine Bacterium
Alteromonas. Genome Biol Evol. 2016 Jun 3;8(5):1556-70. doi: 10.1093/gbe/evw098.

Ivanova EP, López-Pérez M, Webb HK, Ng HJ, Dang TH, Zhukova NV, Mikhailov VV,
Crawford RJ, Rodriguez-Valera F. Thalassospira australica sp. nov. isolated from
sea water. Antonie Van Leeuwenhoek. 2016 Aug;109(8):1091-100. doi:

Rodriguez-Valera F, Martin-Cuadrado AB, López-Pérez M. Flexible genomic
islands as drivers of genome evolution. Curr Opin Microbiol. 2016 Jun;31:154-60.
doi: 10.1016/j.mib.2016.03.014. 

Vavourakis CD, Ghai R, Rodriguez-Valera F, Sorokin DY, Tringe SG, Hugenholtz
P, Muyzer G. Metagenomic Insights into the Uncultured Diversity and Physiology of
Microbes in Four Hypersaline Soda Lake Brines. Front Microbiol. 2016 Feb
25;7:211. doi: 10.3389/fmicb.2016.00211.

Mehrshad M, Amoozegar MA, Ghai R, Shahzadeh Fazeli SA, Rodriguez-Valera F.
Genome Reconstruction from Metagenomic Data Sets Reveals Novel Microbes in the
Brackish Waters of the Caspian Sea. Appl Environ Microbiol. 2016 Jan
4;82(5):1599-612. doi: 10.1128/AEM.03381-15.


Zhang CL, Xie W, Martin-Cuadrado AB, Rodriguez-Valera F. Marine Group II
Archaea, potentially important players in the global ocean carbon cycle. Front
Microbiol. 2015 Oct 13;6:1108. doi: 10.3389/fmicb.2015.01108.

León MJ, Rodríguez-Olmos A, Sánchez-Porro C, López-Pérez M, Rodríguez-Valera
F, Soliveri J, Ventosa A, Copa-Patiño JL. Spiribacter curvatus sp. nov., a
moderately halophilic bacterium isolated from a saltern. Int J Syst Evol
Microbiol. 2015 Dec;65(12):4638-43.

Martin-Cuadrado AB, Pašić L, Rodriguez-Valera F. Diversity of the cell-wall
associated genomic island of the archaeon Haloquadratum walsbyi. BMC Genomics.
2015 Aug 13;16:603. doi: 10.1186/s12864-015-1794-8.

Kimes NE, López-Pérez M, Flores-Félix JD, Ramírez-Bahena MH, Igual JM, Peix
A, Rodriguez-Valera F, Velázquez E. Pseudorhizobium pelagicum gen. nov., sp. nov.
isolated from a pelagic Mediterranean zone. Syst Appl Microbiol. 2015
Jul;38(5):293-9. doi: 10.1016/j.syapm.2015.05.003. 

Carda-Diéguez M, Mizuno CM, Ghai R, Rodriguez-Valera F, Amaro C. Replicating
phages in the epidermal mucosa of the eel (Anguilla anguilla). Front Microbiol.
2015 Jan 29;6:3. doi: 10.3389/fmicb.2015.00003.

Mizuno CM, Rodriguez-Valera F, Ghai R. Genomes of planktonic
Acidimicrobiales: widening horizons for marine Actinobacteria by metagenomics.
MBio. 2015 Feb 10;6(1). pii: e02083-14. doi: 10.1128/mBio.02083-14.

López-Pérez M, Rodriguez-Valera F, Webb HK, Crawford RJ, Ivanova EP.
Correction for López-Pérez et al., Genome Sequence of "Thalassospira australica"
NP3b2T Isolated from St. Kilda Beach, Tasman Sea. Genome Announc. 2015 Jan
22;3(1). pii: e01453-14. doi: 10.1128/genomeA.01453-14.

Martin-Cuadrado AB, Garcia-Heredia I, Moltó AG, López-Úbeda R, Kimes N,
López-García P, Moreira D, Rodriguez-Valera F. A new class of marine
Euryarchaeota group II from the Mediterranean deep chlorophyll maximum. ISME J.
2015 Jul;9(7):1619-34. doi: 10.1038/ismej.2014.249.

Ivanova EP, López-Pérez M, Zabalos M, Nguyen SH, Webb HK, Ryan J, Lagutin K,
Vyssotski M, Crawford RJ, Rodriguez-Valera F. Ecophysiological diversity of a
novel member of the genus Alteromonas, and description of Alteromonas
mediterranea sp. nov. Antonie Van Leeuwenhoek. 2015 Jan;107(1):119-32. doi:


López-Pérez M, Rodriguez-Valera F, Webb HK, Crawford RJ, Ivanova EP. Genome
Sequence of "Thalassospira australica" NP3b2T Isolated from St. Kilda Beach,
Tasman Sea. Genome Announc. 2014 Nov 13;2(6). pii: e01139-14. doi:
10.1128/genomeA.01139-14. PubMed PMID: 25395631; PubMed Central PMCID:

Carda-Diéguez M, Ghai R, Rodriguez-Valera F, Amaro C. Metagenomics of the
mucosal microbiota of European eels. Genome Announc. 2014 Nov 6;2(6). pii:
e01132-14. doi: 10.1128/genomeA.01132-14. PubMed PMID: 25377710; PubMed Central
PMCID: PMC4223461.

Ghai R, Mizuno CM, Picazo A, Camacho A, Rodriguez-Valera F. Key roles for
freshwater Actinobacteria revealed by deep metagenomic sequencing. Mol Ecol. 2014
Dec;23(24):6073-90. doi: 10.1111/mec.12985. PubMed PMID: 25355242.

Kimes NE, López-Pérez M, Ausó E, Ghai R, Rodriguez-Valera F. RNA sequencing
provides evidence for functional variability between naturally co-existing
Alteromonas macleodii lineages. BMC Genomics. 2014 Oct 26;15:938. doi:
10.1186/1471-2164-15-938. PubMed PMID: 25344729; PubMed Central PMCID:

Guo MY, Huo DQ, Ghai R, Rodriguez-Valera F, Shen CH, Zhang N, Zhang SY, Hou
CJ. Metagenomics of ancient fermentation pits used for the production of chinese
strong-aroma liquor. Genome Announc. 2014 Oct 23;2(5). pii: e01045-14. doi:
10.1128/genomeA.01045-14. PubMed PMID: 25342677; PubMed Central PMCID:

Ventosa A, Fernández AB, León MJ, Sánchez-Porro C, Rodriguez-Valera F. The
Santa Pola saltern as a model for studying the microbiota of hypersaline
environments. Extremophiles. 2014 Sep;18(5):811-24. doi:
10.1007/s00792-014-0681-6. Review. PubMed PMID: 25129545.

López-Pérez M, Gonzaga A, Ivanova EP, Rodriguez-Valera F. Genomes of
Alteromonas australica, a world apart. BMC Genomics. 2014 Jun 18;15:483. doi:
10.1186/1471-2164-15-483. PubMed PMID: 24942065; PubMed Central PMCID:

Deschamps P, Zivanovic Y, Moreira D, Rodriguez-Valera F, López-García P.
Pangenome evidence for extensive interdomain horizontal transfer affecting
lineage core and shell genes in uncultured planktonic thaumarchaeota and
euryarchaeota. Genome Biol Evol. 2014 Jun 12;6(7):1549-63. doi:
10.1093/gbe/evu127. PubMed PMID: 24923324; PubMed Central PMCID: PMC4122925.

López-Pérez M, Martin-Cuadrado AB, Rodriguez-Valera F. Homologous
recombination is involved in the diversity of replacement flexible genomic
islands in aquatic prokaryotes. Front Genet. 2014 May 22;5:147. doi:
10.3389/fgene.2014.00147. PubMed PMID: 24904647; PubMed Central PMCID:

Fernández AB, Vera-Gargallo B, Sánchez-Porro C, Ghai R, Papke RT,
Rodriguez-Valera F, Ventosa A. Comparison of prokaryotic community structure from
Mediterranean and Atlantic saltern concentrator ponds by a metagenomic approach.
Front Microbiol. 2014 May 8;5:196. doi: 10.3389/fmicb.2014.00196. PubMed PMID:
24847316; PubMed Central PMCID: PMC4021199.

Park SJ, Ghai R, Martín-Cuadrado AB, Rodríguez-Valera F, Chung WH, Kwon K,
Lee JH, Madsen EL, Rhee SK. Genomes of two new ammonia-oxidizing archaea enriched
from deep marine sediments. PLoS One. 2014 May 5;9(5):e96449. doi:
10.1371/journal.pone.0096449. PubMed PMID: 24798206; PubMed Central PMCID:

León MJ, Fernández AB, Ghai R, Sánchez-Porro C, Rodriguez-Valera F, Ventosa
A. From metagenomics to pure culture: isolation and characterization of the
moderately halophilic bacterium Spiribacter salinus gen. nov., sp. nov. Appl
Environ Microbiol. 2014 Jul;80(13):3850-7. doi: 10.1128/AEM.00430-14. PubMed
PMID: 24747894; PubMed Central PMCID: PMC4054224.

Fernández AB, Ghai R, Martin-Cuadrado AB, Sánchez-Porro C, Rodriguez-Valera
F, Ventosa A. Prokaryotic taxonomic and metabolic diversity of an intermediate
salinity hypersaline habitat assessed by metagenomics. FEMS Microbiol Ecol. 2014
Jun;88(3):623-35. doi: 10.1111/1574-6941.12329. PubMed PMID: 24661078.

Rodriguez-Valera F, Mizuno CM, Ghai R. Tales from a thousand and one phages.
Bacteriophage. 2014 Jan 1;4(1):e28265. PubMed PMID: 24616837; PubMed Central
PMCID: PMC3945994.

Mizuno CM, Ghai R, Rodriguez-Valera F. Evidence for metaviromic islands in
marine phages. Front Microbiol. 2014 Feb 3;5:27. doi: 10.3389/fmicb.2014.00027.
PubMed PMID: 24550898; PubMed Central PMCID: PMC3909814.

Syutkin AS, Pyatibratov MG, Galzitskaya OV, Rodríguez-Valera F, Fedorov OV.
Haloarcula marismortui archaellin genes as ecoparalogs. Extremophiles. 2014
Mar;18(2):341-9. doi: 10.1007/s00792-013-0619-4. PubMed PMID: 24368632.


Mizuno CM, Rodriguez-Valera F, Kimes NE, Ghai R. Expanding the marine
virosphere using metagenomics. PLoS Genet. 2013;9(12):e1003987. doi:
10.1371/journal.pgen.1003987. PubMed PMID: 24348267; PubMed Central PMCID:

Fernandez AB, Ghai R, Martin-Cuadrado AB, Sanchez-Porro C, Rodriguez-Valera
F, Ventosa A. Metagenome sequencing of prokaryotic microbiota from two
hypersaline ponds of a marine saltern in santa pola, Spain. Genome Announc. 2013
Nov 14;1(6). pii: e00933-13. doi: 10.1128/genomeA.00933-13. PubMed PMID:
24233589; PubMed Central PMCID: PMC3828313.

Garcia-Heredia I, Rodriguez-Valera F, Martin-Cuadrado AB. Novel group of
podovirus infecting the marine bacterium Alteromonas macleodii.. Bacteriophage.
2013 Apr 1;3(2):e24766. PubMed PMID: 24228219; PubMed Central PMCID: PMC3821669.

López-Pérez M, Ghai R, Leon MJ, Rodríguez-Olmos Á, Copa-Patiño JL, Soliveri
J, Sanchez-Porro C, Ventosa A, Rodriguez-Valera F. Genomes of "Spiribacter", a
streamlined, successful halophilic bacterium. BMC Genomics. 2013 Nov 13;14:787.
doi: 10.1186/1471-2164-14-787. PubMed PMID: 24225341; PubMed Central PMCID:

Mizuno CM, Kimes NE, López-Pérez M, Ausó E, Rodriguez-Valera F, Ghai R. A
hybrid NRPS-PKS gene cluster related to the bleomycin family of antitumor
antibiotics in Alteromonas macleodii strains. PLoS One. 2013 Sep 19;8(9):e76021.
doi: 10.1371/journal.pone.0076021. PubMed PMID: 24069455; PubMed Central PMCID:

Ghai R, Mizuno CM, Picazo A, Camacho A, Rodriguez-Valera F. Metagenomics
uncovers a new group of low GC and ultra-small marine Actinobacteria. Sci Rep.
2013; 3:2471. doi: 10.1038/srep02471. PubMed PMID: 23959135; PubMed Central PMCID:

López-Pérez M, Gonzaga A, Rodriguez-Valera F. Genomic diversity of "deep
ecotype" Alteromonas macleodii isolates: evidence for Pan-Mediterranean clonal
frames. Genome Biol Evol. 2013; 5(6):1220-32. doi: 10.1093/gbe/evt089. PubMed
PMID: 23729633; PubMed Central PMCID: PMC3698932.

Leon MJ, Ghai R, Fernandez AB, Sanchez-Porro C, Rodriguez-Valera F, Ventosa
A. Draft Genome of Spiribacter salinus M19-40, an Abundant Gammaproteobacterium
in Aquatic Hypersaline Environments. Genome Announc. 2013 Jan;1(1). pii:
e00179-12. doi: 10.1128/genomeA.00179-12. PubMed PMID: 23409269; PubMed Central
PMCID: PMC3569344.

López-Pérez M, Gonzaga A, Martin-Cuadrado AB, López-García P,
Rodriguez-Valera F, Kimes NE. Intra- and intergenomic variation of ribosomal RNA
operons in concurrent Alteromonas macleodii strains. Microb Ecol. 2013
Apr;65(3):720-30. doi: 10.1007/s00248-012-0153-4. PubMed PMID: 23269455.

Mizuno CM, Rodriguez-Valera F, Garcia-Heredia I, Martin-Cuadrado AB, Ghai R.
Reconstruction of novel cyanobacterial siphovirus genomes from Mediterranean
metagenomic fosmids. Appl Environ Microbiol. 2013 Jan;79(2):688-95. doi:
10.1128/AEM.02742-12. PubMed PMID: 23160125; PubMed Central PMCID: PMC3553755.


Gonzaga A, Martin-Cuadrado AB, López-Pérez M, Megumi Mizuno C, García-Heredia
I, Kimes NE, Lopez-García P, Moreira D, Ussery D, Zaballos M, Ghai R,
Rodriguez-Valera F. Polyclonality of concurrent natural populations of
Alteromonas macleodii. Genome Biol Evol. 2012;4(12):1360-74. doi:
10.1093/gbe/evs112. PubMed PMID: 23212172; PubMed Central PMCID: PMC3542563.

Gonzaga A, López-Pérez M, Martin-Cuadrado AB, Ghai R, Rodriguez-Valera F.
Complete genome sequence of the copiotrophic marine bacterium Alteromonas
macleodii strain ATCC 27126T. J Bacteriol. 2012 Dec;194(24):6998. doi:
10.1128/JB.01565-12. PubMed PMID: 23209244; PubMed Central PMCID: PMC3510622.

Park SJ, Kim JG, Jung MY, Kim SJ, Cha IT, Ghai R, Martín-Cuadrado AB,
Rodríguez-Valera F, Rhee SK. Draft genome sequence of an ammonia-oxidizing
archaeon, "Candidatus Nitrosopumilus sediminis" AR2, from Svalbard in the Arctic
Circle. J Bacteriol. 2012 Dec;194(24):6948-9. doi: 10.1128/JB.01869-12. PubMed
PMID: 23209211; PubMed Central PMCID: PMC3510607.

López-Pérez M, Gonzaga A, Martin-Cuadrado AB, Onyshchenko O, Ghavidel A, Ghai
R, Rodriguez-Valera F. Genomes of surface isolates of Alteromonas macleodii: the
life of a widespread marine opportunistic copiotroph. Sci Rep. 2012;2:696. PubMed
PMID: 23019517; PubMed Central PMCID: PMC3458243.

Park SJ, Ghai R, Martín-Cuadrado AB, Rodríguez-Valera F, Jung MY, Kim JG,
Rhee SK. Draft genome sequence of the sulfur-oxidizing bacterium "Candidatus
Sulfurovum sediminum" AR, which belongs to the Epsilonproteobacteria. J
Bacteriol. 2012 Aug;194(15):4128-9. doi: 10.1128/JB.00741-12. PubMed PMID:
22815446; PubMed Central PMCID: PMC3416546.

Ghai R, Hernandez CM, Picazo A, Mizuno CM, Ininbergs K, Díez B, Valas R,
DuPont CL, McMahon KD, Camacho A, Rodriguez-Valera F. Metagenomes of
Mediterranean coastal lagoons. Sci Rep. 2012; 2:490. doi: 10.1038/srep00490.
PubMed PMID: 22778901; PubMed Central PMCID: PMC3391805.

Garcia-Heredia I, Martin-Cuadrado AB, Mojica FJ, Santos F, Mira A, Antón J,
Rodriguez-Valera F. Reconstructing viral genomes from the environment using
fosmid clones: the case of haloviruses. PLoS One. 2012; 7(3):e33802. doi:
10.1371/journal.pone.0033802. PubMed PMID: 22479446; PubMed Central PMCID:

Ghai R, McMahon KD, Rodriguez-Valera F. Breaking a paradigm: cosmopolitan and
abundant freshwater actinobacteria are low GC. Environ Microbiol Rep. 2012
Feb;4(1):29-35. doi: 10.1111/j.1758-2229.2011.00274.x. PubMed PMID: 23757226.

Rodriguez-Valera F, Ussery DW. Is the pan-genome also a pan-selectome?
F1000Res. 2012 Sep 21;1:16. doi: 10.12688/f1000research.1-16.v1. PubMed PMID:
24358823; PubMed Central PMCID: PMC3782348.


Ghai R, Pašić L, Fernández AB, Martin-Cuadrado AB, Mizuno CM, McMahon KD,
Papke RT, Stepanauskas R, Rodriguez-Brito B, Rohwer F, Sánchez-Porro C, Ventosa
A, Rodríguez-Valera F. New abundant microbial groups in aquatic hypersaline
environments. Sci Rep. 2011; 1:135. doi: 10.1038/srep00135. PubMed PMID: 22355652;
PubMed Central PMCID: PMC3216616.

Ghai R, Rodriguez-Valera F, McMahon KD, Toyama D, Rinke R, Cristina Souza de
Oliveira T, Wagner Garcia J, Pellon de Miranda F, Henrique-Silva F. Metagenomics
of the water column in the pristine upper course of the Amazon river. PLoS One.
2011; 6(8):e23785. doi: 10.1371/journal.pone.0023785. Erratum in: PLoS One.
2014;9(5):e97393. PubMed PMID: 21915244; PubMed Central PMCID: PMC3158796.

Brochier-Armanet C, Deschamps P, López-García P, Zivanovic Y,
Rodríguez-Valera F, Moreira D. Complete-fosmid and fosmid-end sequences reveal
frequent horizontal gene transfers in marine uncultured planktonic archaea. ISME
J. 2011 Aug;5(8):1291-302. doi: 10.1038/ismej.2011.16. PubMed PMID: 21346789;
PubMed Central PMCID: PMC3146271.


Mira A, Martín-Cuadrado AB, D'Auria G, Rodríguez-Valera F. The bacterial
pan-genome:a new paradigm in microbiology. Int Microbiol. 2010 Jun;13(2):45-57.
Review. PubMed PMID: 20890839.

Ghai R, Martin-Cuadrado AB, Molto AG, Heredia IG, Cabrera R, Martin J, Verdú
M, Deschamps P, Moreira D, López-García P, Mira A, Rodriguez-Valera F. Metagenome
of the Mediterranean deep chlorophyll maximum studied by direct and fosmid
library 454 pyrosequencing. ISME J. 2010 Sep;4(9):1154-66. doi:
10.1038/ismej.2010.44. PubMed PMID: 20393571.

Rodriguez-Brito B, Li L, Wegley L, Furlan M, Angly F, Breitbart M, Buchanan
J, Desnues C, Dinsdale E, Edwards R, Felts B, Haynes M, Liu H, Lipson D, Mahaffy
J, Martin-Cuadrado AB, Mira A, Nulton J, Pasić L, Rayhawk S, Rodriguez-Mueller J,
Rodriguez-Valera F, Salamon P, Srinagesh S, Thingstad TF, Tran T, Thurber RV,
Willner D, Youle M, Rohwer F. Viral and microbial community dynamics in four
aquatic environments. ISME J. 2010 Jun;4(6):739-51. doi: 10.1038/ismej.2010.1.
PubMed PMID: 20147985.


Pasić L, Rodriguez-Mueller B, Martin-Cuadrado AB, Mira A, Rohwer F,
Rodriguez-Valera F. Metagenomic islands of hyperhalophiles: the case of
Salinibacter ruber. BMC Genomics. 2009 Dec 1;10:570. doi:
10.1186/1471-2164-10-570. PubMed PMID: 19951421; PubMed Central PMCID:

Rodriguez-Valera F, Martin-Cuadrado AB, Rodriguez-Brito B, Pasić L, Thingstad
TF, Rohwer F, Mira A. Explaining microbial population genomics through phage
predation. Nat Rev Microbiol. 2009 Nov;7(11):828-36. doi: 10.1038/nrmicro2235.
PubMed PMID: 19834481.

Martin-Cuadrado AB, Ghai R, Gonzaga A, Rodriguez-Valera F. CO dehydrogenase
genes found in metagenomic fosmid clones from the deep mediterranean sea. Appl
Environ Microbiol. 2009 Dec;75(23):7436-44. doi: 10.1128/AEM.01283-09. PubMed
PMID: 19801465; PubMed Central PMCID: PMC2786428.


Ivars-Martínez E, D'Auria G, Rodríguez-Valera F, Sânchez-Porro C, Ventosa A,
Joint I, Mühling M. Biogeography of the ubiquitous marine bacterium Alteromonas
macleodii determined by multilocus sequence analysis. Mol Ecol. 2008
Sep;17(18):4092-106. PubMed PMID: 19238708.

Ivars-Martinez E, Martin-Cuadrado AB, D'Auria G, Mira A, Ferriera S, Johnson
J, Friedman R, Rodriguez-Valera F. Comparative genomics of two ecotypes of the
marine planktonic copiotroph Alteromonas macleodii suggests alternative
lifestyles associated with different kinds of particulate organic matter. ISME J.
2008 Dec;2(12):1194-212. doi: 10.1038/ismej.2008.74. PubMed PMID: 18670397.

Quaiser A, López-García P, Zivanovic Y, Henn MR, Rodriguez-Valera F, Moreira
D. Comparative analysis of genome fragments of Acidobacteria from deep
Mediterranean plankton. Environ Microbiol. 2008 Oct;10(10):2704-17. doi:
10.1111/j.1462-2920.2008.01691.x. PubMed PMID: 18627413.

Martin-Cuadrado AB, Rodriguez-Valera F, Moreira D, Alba JC, Ivars-Martínez E,
Henn MR, Talla E, López-García P. Hindsight in the relative abundance, metabolic
potential and genome dynamics of uncultivated marine archaea from comparative
metagenomic analyses of bathypelagic plankton of different oceanic regions. ISME
J. 2008 Aug;2(8):865-86. doi: 10.1038/ismej.2008.40. PubMed PMID: 18463691.

Sanchez-Perez G, Mira A, Nyiro G, Pasić L, Rodriguez-Valera F. Adapting to
environmental changes using specialized paralogs. Trends Genet. 2008
Apr;24(4):154-8. doi: 10.1016/j.tig.2008.01.002. Erratum in: Trends Genet. 2008
Jul;24(7):327. PubMed PMID: 18325625.


Cuadros-Orellana S, Martin-Cuadrado AB, Legault B, D'Auria G, Zhaxybayeva O,
Papke RT, Rodriguez-Valera F. Genomic plasticity in prokaryotes: the case of the
square haloarchaeon. ISME J. 2007 Jul;1(3):235-45. PubMed PMID: 18043634.

López-López A, Benlloch S, Bonfá M, Rodríguez-Valera F, Mira A. Intragenomic
16S rDNA divergence in Haloarcula marismortui is an adaptation to different
temperatures. J Mol Evol. 2007 Dec;65(6):687-96. PubMed PMID: 18026684.

Martín-Cuadrado AB, López-García P, Alba JC, Moreira D, Monticelli L,
Strittmatter A, Gottschalk G, Rodríguez-Valera F. Metagenomics of the deep
Mediterranean, a warm bathypelagic habitat. PLoS One. 2007 Sep 19;2(9):e914.
PubMed PMID: 17878949; PubMed Central PMCID: PMC1976395.

Sharma AK, Walsh DA, Bapteste E, Rodriguez-Valera F, Ford Doolittle W, Papke
RT. Evolution of rhodopsin ion pumps in haloarchaea. BMC Evol Biol. 2007 May
18;7:79. PubMed PMID: 17511874; PubMed Central PMCID: PMC1885257.

Burns DG, Janssen PH, Itoh T, Kamekura M, Li Z, Jensen G, Rodríguez-Valera F,
Bolhuis H, Dyall-Smith ML. Haloquadratum walsbyi gen. nov., sp. nov., the square
haloarchaeon of Walsby, isolated from saltern crystallizers in Australia and
Spain. Int J Syst Evol Microbiol. 2007 Feb;57(Pt 2):387-92. PubMed PMID:


Legault BA, Lopez-Lopez A, Alba-Casado JC, Doolittle WF, Bolhuis H,
Rodriguez-Valera F, Papke RT. Environmental genomics of "Haloquadratum walsbyi"
in a saltern crystallizer indicates a large pool of accessory genes in an
otherwise coherent species. BMC Genomics. 2006 Jul 4;7:171. PubMed PMID:
16820057; PubMed Central PMCID: PMC1560387.

Bolhuis H, Palm P, Wende A, Falb M, Rampp M, Rodriguez-Valera F, Pfeiffer F,
Oesterhelt D. The genome of the square archaeon Haloquadratum walsbyi : life at
the limits of water activity. BMC Genomics. 2006 Jul 4;7:169. PubMed PMID:
16820047; PubMed Central PMCID: PMC1544339.

Zaballos M, López-López A, Ovreas L, Bartual SG, D'Auria G, Alba JC, Legault
B, Pushker R, Daae FL, Rodríguez-Valera F. Comparison of prokaryotic diversity at
offshore oceanic locations reveals a different microbiota in the Mediterranean
Sea. FEMS Microbiol Ecol. 2006 Jun;56(3):389-405. PubMed PMID: 16689872.

Mira A, Pushker R, Rodríguez-Valera F. The Neolithic revolution of bacterial
genomes. Trends Microbiol. 2006 May;14(5):200-6. Review. PubMed PMID: 16569502.

Moreira D, Rodríguez-Valera F, López-García P. Metagenomic analysis of
mesopelagic Antarctic plankton reveals a novel deltaproteobacterial group.
Microbiology. 2006 Feb;152(Pt 2):505-17. PubMed PMID: 16436438.

D'Auria G, Pushker R, Rodriguez-Valera F. IWoCS: analyzing ribosomal
intergenic transcribed spacers configuration and taxonomic relationships.
Bioinformatics. 2006 Mar 1;22(5):527-31. PubMed PMID: 16403794.


Mongodin EF, Nelson KE, Daugherty S, Deboy RT, Wister J, Khouri H, Weidman J,
Walsh DA, Papke RT, Sanchez Perez G, Sharma AK, Nesbø CL, MacLeod D, Bapteste E,
Doolittle WF, Charlebois RL, Legault B, Rodriguez-Valera F. The genome of
Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria
and archaea. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18147-52. PubMed PMID:
16330755; PubMed Central PMCID: PMC1312414.

Onyshchenko OM, Kiprianova OA, Rodriguez-Valera F, Benlloch S. [Taxonomical
study of bacteria from genera Alteromonas and Pseudoalteromonas isolated from
Black Sea water and invertebrates]. Mikrobiol Z. 2005 Jul-Aug;67(4):3-13.
Ukrainian. PubMed PMID: 16250230.

Pushker R, D'Auria G, Alba-Casado JC, Rodríguez-Valera F. Micro-Mar: a
database for dynamic representation of marine microbial biodiversity. BMC
Bioinformatics. 2005 Sep 9;6:222. PubMed PMID: 16153293; PubMed Central PMCID:

Bartual SG, Seifert H, Hippler C, Luzon MA, Wisplinghoff H, Rodríguez-Valera
F. Development of a multilocus sequence typing scheme for characterization of
clinical isolates of Acinetobacter baumannii. J Clin Microbiol. 2005
Sep;43(9):4382-90. Erratum in: J Clin Microbiol. 2007 Jun;45(6):2101. PubMed
PMID: 16145081; PubMed Central PMCID: PMC1234098.

López-López A, Bartual SG, Stal L, Onyshchenko O, Rodríguez-Valera F. Genetic
analysis of housekeeping genes reveals a deep-sea ecotype of Alteromonas
macleodii in the Mediterranean Sea. Environ Microbiol. 2005 May;7(5):649-59.
PubMed PMID: 15819847.


Papke RT, Koenig JE, Rodríguez-Valera F, Doolittle WF. Frequent recombination
in a saltern population of Halorubrum. Science. 2004 Dec 10;306(5703):1928-9.
PubMed PMID: 15591201.

Mira A, Pushker R, Legault BA, Moreira D, Rodríguez-Valera F. Evolutionary
relationships of Fusobacterium nucleatum based on phylogenetic analysis and
comparative genomics. BMC Evol Biol. 2004 Nov 26;4:50. PubMed PMID: 15566569;
PubMed Central PMCID: PMC535925.

Bolhuis H, Poele EM, Rodriguez-Valera F. Isolation and cultivation of
Walsby's square archaeon. Environ Microbiol. 2004 Dec;6(12):1287-91. PubMed PMID:

Moreira D, Rodríguez-Valera F, López-García P. Analysis of a genome fragment
of a deep-sea uncultivated Group II euryarchaeote containing 16S rDNA, a
spectinomycin-like operon and several energy metabolism genes. Environ Microbiol.
2004 Sep;6(9):959-69. PubMed PMID: 15305921.

Pushker R, Mira A, Rodríguez-Valera F. Comparative genomics of gene-family
size in closely related bacteria. Genome Biol. 2004;5(4):R27. PubMed PMID:
15059260; PubMed Central PMCID: PMC395786.

Rodríguez-Valera F. Environmental genomics, the big picture? FEMS Microbiol
Lett. 2004 Feb 16;231(2):153-8. Review. PubMed PMID: 15027428.

López-García P, Brochier C, Moreira D, Rodríguez-Valera F. Comparative
analysis of a genome fragment of an uncultivated mesopelagic crenarchaeote
reveals multiple horizontal gene transfers. Environ Microbiol. 2004
Jan;6(1):19-34. PubMed PMID: 14686938.


Papke RT, Douady CJ, Doolittle WF, Rodríguez-Valera F. Diversity of
bacteriorhodopsins in different hypersaline waters from a single Spanish saltern.
Environ Microbiol. 2003 Nov;5(11):1039-45. PubMed PMID: 14641583.

Ruiz M, Rodríguez JC, Rodríguez-Valera F, Royo G. Amplified-fragment length
polymorphism as a complement to IS6110-based restriction fragment length
polymorphism analysis for molecular typing of Mycobacterium tuberculosis. J Clin
Microbiol. 2003 Oct;41(10):4820-2. PubMed PMID: 14532231; PubMed Central PMCID:

Cifuentes A, Antón J, De Wit R, Rodríguez-Valera F. Diversity of bacteria and
Archaea in sulphate-reducing enrichment cultures inoculated from serial dilution
of Zostera noltii rhizosphere samples. Environ Microbiol. 2003 Sep;5(9):754-64.
PubMed PMID: 12919411.

Øvreås L, Daae FL, Torsvik V, Rodríguez-Valera F. Characterization of
microbial diversity in hypersaline environments by melting profiles and
reassociation kinetics in combination with terminal restriction fragment length
polymorphism (T-RFLP). Microb Ecol. 2003 Oct;46(3):291-301. PubMed PMID:


Rodríguez-Valera F. Approaches to prokaryotic biodiversity: a population
genetics perspective. Environ Microbiol. 2002 Nov;4(11):628-33. Review. PubMed
PMID: 12460270.

Pérez-Luz S, Fernandez J, Rodríguez-Valera F, Pascual L, Moreno C, Amo A,
Apraiz D, Catalán V. Sequence diversity of the internal transcribed spacer (ITS)
region of the rRNA operons among different serogroups of Legionella pneumophila
isolates. Syst Appl Microbiol. 2002 Aug;25(2):212-9. PubMed PMID: 12353875.

López-López A, Pujalte MJ, Benlloch S, Mata-Roig M, Rosselló-Mora R, Garay E,
Rodríguez-Valera F. Thalassospira lucentensis gen. nov., sp. nov., a new marine
member of the alpha-Proteobacteria. Int J Syst Evol Microbiol. 2002 Jul;52(Pt
4):1277-83. PubMed PMID: 12148640.

Such J, Francés R, Muñoz C, Zapater P, Casellas JA, Cifuentes A,
Rodríguez-Valera F, Pascual S, Sola-Vera J, Carnicer F, Uceda F, Palazón JM,
Pérez-Mateo M. Detection and identification of bacterial DNA in patients with
cirrhosis and culture-negative, nonneutrocytic ascites. Hepatology. 2002
Jul;36(1):135-41. PubMed PMID: 12085357.

Benlloch S, López-López A, Casamayor EO, Øvreås L, Goddard V, Daae FL,
Smerdon G, Massana R, Joint I, Thingstad F, Pedrós-Alió C, Rodríguez-Valera F.
Prokaryotic genetic diversity throughout the salinity gradient of a coastal solar
saltern. Environ Microbiol. 2002 Jun;4(6):349-60. PubMed PMID: 12071980.

Casamayor EO, Massana R, Benlloch S, Øvreås L, Díez B, Goddard VJ, Gasol JM,
Joint I, Rodríguez-Valera F, Pedrós-Alió C. Changes in archaeal, bacterial and
eukaryal assemblages along a salinity gradient by comparison of genetic
fingerprinting methods in a multipond solar saltern. Environ Microbiol. 2002
Jun;4(6):338-48. PubMed PMID: 12071979.

García-Martínez J, Acinas SG, Massana R, Rodríguez-Valera F. Prevalence and
microdiversity of Alteromonas macleodii-like microorganisms in different oceanic
regions. Environ Microbiol. 2002 Jan;4(1):42-50. PubMed PMID: 11966824.

Antón J, Oren A, Benlloch S, Rodríguez-Valera F, Amann R, Rosselló-Mora R.
Salinibacter ruber gen. nov., sp. nov., a novel, extremely halophilic member of
the Bacteria from saltern crystallizer ponds. Int J Syst Evol Microbiol. 2002
Mar;52(Pt 2):485-91. PubMed PMID: 11931160.

Ruiz M, Rodríguez JC, García-Martínez J, Escribano I, Sirvent E, Gutiérrez
F, Rodríguez-Valera F, Royo G. Molecular characterization of a Spanish isolate of
Mycobacterium malmoense. Res Microbiol. 2002 Jan-Feb;153(1):33-6. PubMed PMID:

López-García P, Rodríguez-Valera F, Moreira D. Toward the monophyly of
Haeckel's radiolaria: 18S rRNA environmental data support the sisterhood of
polycystinea and acantharea. Mol Biol Evol. 2002 Jan;19(1):118-21. PubMed PMID:


Ruíz M, Rodríguez JC, Escribano I, García-Martínez J, Rodríguez-Valera F,
Royo G. Application of molecular biology techniques to the diagnosis of
nontuberculous mycobacterial infections. APMIS. 2001 Dec;109(12):857-64. PubMed
PMID: 11846727.

Moreira D, López-García P, Rodríguez-Valera F. New insights into the
phylogenetic position of diplonemids: G+C content bias, differences of
evolutionary rate and a new environmental sequence. Int J Syst Evol Microbiol.
2001 Nov;51(Pt 6):2211-9. PubMed PMID: 11760964.

Anton AI, Martinez-Murcia AJ, Rodriguez-Valera F, Dalet F. Sequence
microdiversity at the ribosomal RNA operons of Escherichia coli
pyelonephritogenic strains. Clin Microbiol Infect. 2001 Jul;7(7):345-51. PubMed
PMID: 11531978.

López-García P, López-López A, Moreira D, Rodríguez-Valera F. Diversity of
free-living prokaryotes from a deep-sea site at the Antarctic Polar Front. FEMS
Microbiol Ecol. 2001 Jul;36(2-3):193-202. PubMed PMID: 11451524.

Oren A, Rodríguez-Valera F. The contribution of halophilic Bacteria to the
red coloration of saltern crystallizer ponds(1). FEMS Microbiol Ecol. 2001
Jul;36(2-3):123-130. PubMed PMID: 11451516.

Benlloch S, Acinas SG, Antón J, López-López A, Luz SP, Rodríguez-Valera F.
Archaeal Biodiversity in Crystallizer Ponds from a Solar Saltern: Culture versus
PCR. Microb Ecol. 2001 Jan;41(1):12-19. PubMed PMID: 11252160.

López-García P, Moreira D, López-López A, Rodríguez-Valera F. A novel
haloarchaeal-related lineage is widely distributed in deep oceanic regions.
Environ Microbiol. 2001 Jan;3(1):72-8. PubMed PMID: 11225725.

López-García P, Rodríguez-Valera F, Pedrós-Alió C, Moreira D. Unexpected
diversity of small eukaryotes in deep-sea Antarctic plankton. Nature. 2001 Feb
1;409(6820):603-7. PubMed PMID: 11214316.

García-Martínez J, Bescós I, Rodríguez-Sala JJ, Rodríguez-Valera F. RISSC: a
novel database for ribosomal 16S-23S RNA genes spacer regions. Nucleic Acids Res.
2001 Jan 1;29(1):178-80. PubMed PMID: 11125084; PubMed Central PMCID: PMC29764.


Moreira D, Rodríguez-Valera F. A mitochondrial origin for eukaryotic C2H2
zinc finger regulators? Trends Microbiol. 2000 Oct;8(10):448-50. PubMed PMID:

Rodríguez JC, Royo G, Rodríguez-Valera F. Application of four molecular
techniques for typing outbreak-associated Mycobacterium tuberculosis strains.
APMIS. 2000 Mar;108(3):231-6. PubMed PMID: 10752693.

Díez B, Antón J, Guixa-Boixereu N, Pedrós-Alió C, Rodríguez-Valera F.
Pulsed-field gel electrophoresis analysis of virus assemblages present in a
hypersaline environment. Int Microbiol. 2000 Sep;3(3):159-64. PubMed PMID:

García-Martínez J, Rodríguez-Valera F. Microdiversity of uncultured marine
prokaryotes: the SAR11 cluster and the marine Archaea of Group I. Mol Ecol. 2000
Jul;9(7):935-48. PubMed PMID: 10886656.

Antón J, Rosselló-Mora R, Rodríguez-Valera F, Amann R. Extremely halophilic
bacteria in crystallizer ponds from solar salterns. Appl Environ Microbiol. 2000
Jul;66(7):3052-7. PubMed PMID: 10877805; PubMed Central PMCID: PMC92110.

Cifuentes A, Antón J, Benlloch S, Donnelly A, Herbert RA, Rodríguez-Valera
F. Prokaryotic diversity in Zostera noltii-colonized marine sediments. Appl
Environ Microbiol. 2000 Apr;66(4):1715-9. PubMed PMID: 10742267; PubMed Central
PMCID: PMC92048.


Antón J, Llobet-Brossa E, Rodríguez-Valera F, Amann R. Fluorescence in situ
hybridization analysis of the prokaryotic community inhabiting crystallizer
ponds. Environ Microbiol. 1999 Dec;1(6):517-23. PubMed PMID: 11207773.

Parolis LA, Parolis H, Paramonov NA, Boán IF, Antón J, Rodríguez-Valera F.
Structural studies on the acidic exopolysaccharide from Haloferax denitrificans
ATCC 35960. Carbohydr Res. 1999 Jun 30;319(1-4):133-40. PubMed PMID: 10520261.

García-Martínez J, Acinas SG, Antón AI, Rodríguez-Valera F. Use of the
16S--23S ribosomal genes spacer region in studies of prokaryotic diversity. J
Microbiol Methods. 1999 May;36(1-2):55-64. PubMed PMID: 10353800.

Martínez-Murcia AJ, Antón AI, Rodríguez-Valera F. Patterns of sequence
variation in two regions of the 16S rRNA multigene family of Escherichia coli.
Int J Syst Bacteriol. 1999 Apr;49 Pt 2:601-10. PubMed PMID: 10319482.

Antón AI, Martínez-Murcia AJ, Rodríguez-Valera F. Intraspecific diversity of
the 23S rRNA gene and the spacer region downstream in Escherichia coli. J
Bacteriol. 1999 May;181(9):2703-9. PubMed PMID: 10217757; PubMed Central PMCID:

Hurtado A, Rodríguez-Valera F. Accessory DNA in the genomes of
representatives of the Escherichia coli reference collection. J Bacteriol. 1999
Apr;181(8):2548-54. PubMed PMID: 10198021; PubMed Central PMCID: PMC93683.

Lopez-Lopez A, Exposito E, Anton J, Rodriguez-Valera F, Aldaz A. Use of
thiobacillus ferrooxidans in a coupled microbiological-electrochemical system for
wastewater detoxification . Biotechnol Bioeng. 1999 Apr 5;63(1):79-86. PubMed
PMID: 10099583.

Acinas SG, Antón J, Rodríguez-Valera F. Diversity of free-living and
attached bacteria in offshore Western Mediterranean waters as depicted by
analysis of genes encoding 16S rRNA. Appl Environ Microbiol. 1999
Feb;65(2):514-22. PubMed PMID: 9925576; PubMed Central PMCID: PMC91055.


Paramonov NA, Parolis LA, Parolis H, Boán IF, Antón J, Rodríguez-Valera F.
The structure of the exocellular polysaccharide produced by the Archaeon
Haloferax gibbonsii (ATCC 33959). Carbohydr Res. 1998 Jun;309(1):89-94. PubMed
PMID: 9720239.

Antón AI, Martínez-Murcia AJ, Rodríguez-Valera F. Sequence diversity in the
16S-23S intergenic spacer region (ISR) of the rRNA operons in representatives of
the Escherichia coli ECOR collection. J Mol Evol. 1998 Jul;47(1):62-72. PubMed
PMID: 9664697.

Pérez Luz S, Rodríguez-Valera F, Lan R, Reeves PR. Variation of the
ribosomal operon 16S-23S gene spacer region in representatives of Salmonella
enterica subspecies. J Bacteriol. 1998 Apr;180(8):2144-51. PubMed PMID: 9555898;
PubMed Central PMCID: PMC107142.


Mojica FJ, Cisneros E, Ferrer C, Rodríguez-Valera F, Juez G. Osmotically
induced response in representatives of halophilic prokaryotes: the bacterium
Halomonas elongata and the archaeon Haloferax volcanii. J Bacteriol. 1997
Sep;179(17):5471-81. PubMed PMID: 9287003; PubMed Central PMCID: PMC179419.

Zavaleta AI, Martínez-Murcia AJ, Rodríguez-Valera F. Intraspecific genetic
diversity of Oenococcus oeni as derived from DNA fingerprinting and sequence
analyses. Appl Environ Microbiol. 1997 Apr;63(4):1261-7. PubMed PMID: 9097422;
PubMed Central PMCID: PMC168419.


Parolis H, Parolis LA, Boán IF, Rodríguez-Valera F, Widmalm G, Manca MC,
Jansson PE, Sutherland IW. The structure of the exopolysaccharide produced by the
halophilic Archaeon Haloferax mediterranei strain R4 (ATCC 33500). Carbohydr Res.
1996 Dec 13;295:147-56. PubMed PMID: 9002190.

García-Martínez J, Martínez-Murcia A, Antón AI, Rodríguez-Valera F.
Comparison of the small 16S to 23S intergenic spacer region (ISR) of the rRNA
operons of some Escherichia coli strains of the ECOR collection and E. coli K-12.
J Bacteriol. 1996 Nov;178(21):6374-7. PubMed PMID: 8892845; PubMed Central PMCID:

Zavaleta AI, Martínez-Murcia AJ, Rodríguez-Valera F. 16S-23S rDNA intergenic
sequences indicate that Leuconostoc oenos is phylogenetically homogeneous.
Microbiology. 1996 Aug;142 ( Pt 8):2105-14. PubMed PMID: 8760923.

García-Martínez J, Martínez-Murcia AJ, Rodríguez-Valera F, Zorraquino A.
Molecular evidence supporting the existence of two major groups in uropathogenic
Escherichia coli. FEMS Immunol Med Microbiol. 1996 Jul;14(4):231-44. PubMed PMID:

Ferrer C, Mojica FJ, Juez G, Rodríguez-Valera F. Differentially transcribed
regions of Haloferax volcanii genome depending on the medium salinity. J
Bacteriol. 1996 Jan;178(1):309-13. PubMed PMID: 8550436; PubMed Central PMCID:


Rodríguez-Valera F, García Martínez J, Martínez-Murcia AJ. Intraspecific
diversity in Bacteria. The case of Escherichia coli. Microbiologia. 1995
Sep;11(3):379-82. PubMed PMID: 7576356.

Mojica FJ, Ferrer C, Juez G, Rodríguez-Valera F. Long stretches of short
tandem repeats are present in the largest replicons of the Archaea Haloferax
mediterranei and Haloferax volcanii and could be involved in replicon
partitioning. Mol Microbiol. 1995 Jul;17(1):85-93. PubMed PMID: 7476211.


Martínez-Murcia AJ, Rodríguez-Valera F. The use of arbitrarily primed PCR
(AP-PCR) to develop taxa specific DNA probes of known sequence. FEMS Microbiol
Lett. 1994 Dec 15;124(3):265-9. PubMed PMID: 7851733.

Mojica FJ, Charbonnier F, Juez G, Rodríguez-Valera F, Forterre P. Effects of
salt and temperature on plasmid topology in the halophilic archaeon Haloferax
volcanii. J Bacteriol. 1994 Aug;176(16):4966-73. PubMed PMID: 8051009; PubMed
Central PMCID: PMC196334.


Mojica FJ, Juez G, Rodríguez-Valera F. Transcription at different salinities
of Haloferax mediterranei sequences adjacent to partially modified PstI sites.
Mol Microbiol. 1993 Aug;9(3):613-21. PubMed PMID: 8412707.

Rodriguez-Valera F. Biotechnological potential of halobacteria. Biochem Soc
Symp. 1992;58:135-47. Review. PubMed PMID: 1445403.


Juez G, Rodriguez-Valera F, Herrero N, Mojica FJ. Evidence for
salt-associated restriction pattern modifications in the archaeobacterium
Haloferax mediterranei. J Bacteriol. 1990 Dec;172(12):7278-81. PubMed PMID:
1979325; PubMed Central PMCID: PMC210857.

Lillo JG, Rodriguez-Valera F. Effects of Culture Conditions on
Poly(beta-Hydroxybutyric Acid) Production by Haloferax mediterranei. Appl Environ
Microbiol. 1990 Aug;56(8):2517-2521. PubMed PMID: 16348261; PubMed Central PMCID:


Antón J, Meseguer I, Rodríguez-Valera F. Production of an Extracellular
Polysaccharide by Haloferax mediterranei. Appl Environ Microbiol. 1988
Oct;54(10):2381-6. PubMed PMID: 16347749; PubMed Central PMCID: PMC204266.


Pérez-Fillol M, Rodríguez-Valera F. Potassium ion accumulation in cells of
different halobacteria. Microbiologia. 1986 Oct;2(2):73-80. PubMed PMID: 3271061.

Fernandez-Castillo R, Rodriguez-Valera F, Gonzalez-Ramos J, Ruiz-Berraquero
F. Accumulation of Poly (beta-Hydroxybutyrate) by Halobacteria. Appl Environ
Microbiol. 1986 Jan;51(1):214-6. PubMed PMID: 16346972; PubMed Central PMCID:


Pérez-Fillol M, Rodríguez-Valera F, Ferry JG. Isolation of methanogenic
bacteria able to grow in high salt concentration. Microbiologia. 1985
Sep;1(1-2):29-33. PubMed PMID: 3939840.

Rodriguez-Valera F, Ventosa A, Juez G, Imhoff JF. Variation of environmental
features and microbial populations with salt concentrations in a multi-pond
saltern. Microb Ecol. 1985 Jun;11(2):107-15. doi: 10.1007/BF02010483. PubMed
PMID: 24221299.


Imhoff JF, Rodriguez-Valera F. Betaine is the main compatible solute of
halophilic eubacteria. J Bacteriol. 1984 Oct;160(1):478-9. PubMed PMID: 6148337;
PubMed Central PMCID: PMC214750.


Rodriguez-Valera F, Nieto JJ, Ruiz-Berraquero F. Light as an energy source
in continuous cultures of bacteriorhodopsin-containing halobacteria. Appl Environ
Microbiol. 1983 Mar;45(3):868-71. PubMed PMID: 16346250; PubMed Central PMCID:

Rodriguez-Valera F, Juez G, Kushner DJ. Halobacterium mediterranei spec,
nov., a New Carbohydrate-Utilizing Extreme Halophile. Syst Appl Microbiol.
1983; 4(3):369-81. doi: 10.1016/S0723-2020(83)80021-6. PubMed PMID: 23194735.


Rodriguez-Valera F, Ruiz-Berraquero F, Ramos-Cormenzana A. Characteristics
of the heterotrophic bacterial populations in hypersaline environments of
different salt concentrations. Microb Ecol. 1981 Sep;7(3):235-43. doi:
10.1007/BF02010306. PubMed PMID: 24227498.


Rodriguez-Valera F, Ruiz-Berraquero F, Ramos-Cormenzana A. Behaviour of
mixed populations of halophilic bacteria in continuous cultures. Can J Microbiol.
1980 Nov;26(11):1259-63. PubMed PMID: 7214216.


Rodriguez-Valera F, Ruiz-Berraquero F, Ramos-Cormenzana A. Isolation of
extreme halophiles from seawater. Appl Environ Microbiol. 1979 Jul;38(1):164-5.
PubMed PMID: 16345409; PubMed Central PMCID: PMC243452.